Why uterus transplants fail?
#Cosmoread: First uterus transplant in the United States has been fired just weeks after the procedure, and only a handful of these operations have been performed successfully in other countries. So what makes it so challenging uterus transplant, and that’s why they can fail?
Wednesday (9 March), at the Cleveland Clinic announced that its uterus transplant patient who had received a transplanted organ suddenly experience the complexity and had to be removed. At the start of the implant in a 9-hour surgery, was performed on February 25th.
Doctors implanted complications that led to the removal of the uterus did not provide information. However, the Cleveland Clinic said in a statement that it was reviewing the matter and that it will provide more information as it became available. “Medical team to ensure the safety of our patients took all necessary precautions and measures,” the statement said.
So far, there have been 12 in the world uterus transplant, and five were not successful. This is normal uterus transplant fails for any organ transplant can fail, said Dr. Alexander Maskin, University of Nebraska Medical Center (UNMC), assistant professor of surgery at the Cleveland Clinic case UNMC was not involved but who is helping to plan a uterus transplant program.
The main reasons for rejection of organ failure, which is when the patient’s immune system attacks part include; Part of the transition; Or problems with the blood supply to the organ. In the case of a uterus transplant, impaired blood clot can block blood flow or in part, Maskin said.
A woman who received organ transplants in 2000 in Saudi Arabia, a uterus removed after about three months of the initial operation is needed. In that case, the organs deteriorate because clots blocking its blood supply. Another woman in Turkey in 2011 a deceased donor transplant a uterus received, and he was able to become pregnant, but miscarried. More recently, in Sweden, nine uterus transplant doctors, and the two had to be removed after surgery. But Swedish women get pregnant and give birth five were able to.
Swedish test, transplanted uteruses, came from living donors, while patients at the Cleveland Clinic, a uterus transplant came from a deceased donor. It is clear that living organ donors may affect the success of a uterus transplant versus not using the deceased, Maskin said, noting that the uterus transplants from deceased donors has received only two women. “[It’s] too early to speculate,” Maskin said.
The main challenge is that uterine transplant surgery is very new, so it will take time to correct.
“It’s much more difficult [than other implants] No, it’s just that it’s a new surgery, so the learning curve of figuring out how exactly to do it standing” Maskin said. He said that, three decades ago, the kidney transplant took 6 to 10 hours to complete, but can be done in an hour and a half.